Is Retinyl Palmitate Absorbed?

Retinoids are a family of topical vitamin A derivatives. A popular over-the-counter retinoid is retinol. A commonly prescribed retinoid is tretinoin, better known under the brand name Retin-A. Retinoids are used to help the skin appear more youthful. Retinoids aid the skin by penetrating the skin to increase cell turnover, which causes the skin to feel smoother and look brighter with continued usage. They also help to build collagen and thicken the skin, which reduces fine line and wrinkles.

Everyone wants to use ingredients on their skin that can help them to look their best. However, not all ingredients are well tolerated by all skin types. Unfortunately, retinols and tretinoin can have side effects. Some common side effects include redness, flaking, peeling, and sun sensitivity. These unwanted results can sometimes deter users from continuing with treatment.

Since retinoids are all related, they can be metabolized or oxidized into one another by changing their molecular structure. Retinyl palmitate is another vitamin A deriviative. It can be metabolized to retinol and subsequently to retinoic acid. This is important to note, because both retinol and tretinoin are metabolized into retinoic acid in the skin, as well. Also noteworthy is that retinyl palmitate does not have any of the unwanted side effects that both retinol and tretinoin can cause. Could retinyl palmitate offer the same benefits without any of the potential side effects? A recent study found the answer.

An article in the “The Journal of Invetigative Dermatology” reported on a study that investigated the effects of the various retinoids on the skin. Their results were outlined in the article, “Unoccluded Retinol Penetrates Human Skin In Vivo More Effectively than Unoccluded Retinyl Palmitate or Retinoic Acid”. Study findings reported that, “In the second series, biopsy samples were obtained 4 d after a single application of vehicle or 0.1%, 0.3% and 0.6% palmitate or 0.6% ROL Palm. The data indicate that at a concentration of 0.6% ROL Palm there is a statistically significant induction of RA 4-OHase in comparison to activity in vehicle-treated areas.”  Taking that information and going a step further, they went on to conclude that, “ROL Palm without occlusion gave results similar to 0.1% RA in cream vehicle without occlusion.” Simply stated, retinyl palmitate had the same positive effects on the skin as retinoic acid. This is a revolutionary discovery for people that cannot tolerate the redness and peeling that occurs when using retinol or tretinoin.

Cloud Vitamin Cream’s Retinyl Palmitate offers a wonderful alternative to other retinoids. Cloud’s Retinyl Palmitate produces the same clinical benefits as retinol or prescription tretinoin without the irritating side effects. For those who want more youthful skin, but don’t want to experience the sensitivities that other topical retinoids cause, Clouds’s Retinyl Palmitate is the perfect solution.
July 15, 2014 by Cathy Mohr
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